A sequel to 2019's Joker, Joker: Folie à Deux will see Phoenix reprise his role as the Clown Prince of Crime, while Lady Gaga is playing Dr. Harleen Quinzel/Harley Quinn. Zazie Beetz is also Harley Quinn. Harley Quinn has finally broken things off once and for all with the Joker, and attempts to make it on her own as the criminal Queenpin of Gotham City. The series features Harley Quinn, Poison Ivy and a whole cast of heroes and villains, old and new, from the DC Universe. New Joker: Folie à Deux set photos give a better look at Lady Gaga's Harley Quinn in the movie. The film is a sequel to 2019's Joker, which became the highest-grossing R-rated movie of all-time, and amassed a number of important awards, including a Best Actor win for star Joaquin Phoenix at the Oscars. Now, Joker: Folie à Deux is going bigger DC's animated Harley Quinn series is now streaming on HBO Max. Harley Quinn review: DC comedy needs so many more seasons. Harley Quinn pokes fun at fanboys in exclusive clip. Harley Quinn Joker 2 Director Shares New Look at Joaquin Phoenix and Lady Gaga as Joker and Harley Quinn. Joker: Folie á Deux cinematographer, Lawrence Sher, reveals the film is almost ready and promises it Quinn has previously been played onscreen by Margot Robbie in the DC Extended Universe while Kaley Cuoco voices her in her own animated series, called Harley Quinn. Gaga will likely play Harley Quinn in "Joker 2." "Joker" made over $1 billion at the box office in 2019. Phoenix at the EE British Academy Film Awards at Royal Albert Hall in 2020 in London. The upcoming movie Joker: Folie à Deux is the highly anticipated sequel to the 2019 hit movie Joker.At the heart of the film is Lady Gaga's portrayal of Harley Quinn, one of the most iconic and AR7DxTL.